Regenerative skin booster · Myeongdong, Seoul
PDRN Injection Myeongdong Seoul: calmer, stronger skin, from the inside.
A regenerative injection of purified DNA fragments that supports skin repair, calms redness and improves texture and elasticity. Performed by licensed physicians at RE:BERRY Myeongdong, two minutes from Myeongdong Station Exit 8, with consultations in your language.
Medically reviewed by Dr. Seung-Jae Baek, Chief Medical Director (licence No. 143338) · Updated 8 October 2026
Quick answer · What is PDRN Injection?
PDRN (polydeoxyribonucleotide) injection is a regenerative skin booster made from purified salmon DNA fragments. Injected into the dermis, PDRN is thought to act on adenosine A2A receptors, supporting tissue repair and reducing inflammation. It is used for sensitive, damaged or ageing skin and after lasers. A session takes 30–45 minutes with numbing, with mild redness for hours, and a course is usually 3–5 sessions two to three weeks apart.
- Session
- 30–45 min
- Downtime
- Mild redness for hours
- Results
- After 2–3 sessions
- Course
- 3–5 sessions, 2–3 weeks apart
How it works
Supporting the skin's own repair signals
PDRN is a short-chain DNA fragment that binds adenosine A2A receptors in the skin. This is associated with growth-factor release, reduced inflammation and better micro-circulation, which help damaged or stressed skin recover. Over a course, the skin barrier tends to become calmer and texture more even.
-
Skin check & numbing
Your doctor reviews your skin concerns, cleanses the area and applies numbing cream for about 20–30 minutes.
-
Even injections
PDRN is placed across the face by fine-needle micro-injections or an injector device, at a shallow dermal depth.
-
Recovery & renewal
Redness and bumps fade within hours to a day. Calmness and texture improve over the course, often clearest after the third session.
Before & after
Calmer tone, smoother texture
Patients most often notice less redness and sensitivity, better hydration and a smoother surface, building gradually across a course of sessions.
Photos published with patient consent. Results vary between individuals and are not a guarantee of outcome.
A good fit if you…
- Have sensitive, reactive skin or a weakened barrier
- Want to support recovery after laser, peels or acne
- Notice dullness, fine lines or a loss of bounce
- Prefer a gentle booster with short downtime
Talk to your doctor first if you…
- Are pregnant or breastfeeding
- Have a fish or salmon allergy
- Take blood thinners or have a bleeding disorder
- Have an active skin infection or cold sore in the area
Compare options
How PDRN Injection compares with similar treatments
| Treatment | How it works | Session | Downtime |
|---|---|---|---|
| PDRN Injection | PDRN regenerative injections | 30–45 min | Mild redness for hours |
| Rejuran Healer | Polynucleotide (PN) injections | 45–60 min | Small bumps, 1–2 days |
| Rejuran i | PN injections for the eye area | 20–30 min | Small bumps 1–2 days |
| Salmon DNA Injection | Salmon DNA (PN/PDRN) injections | 30–45 min | Small bumps about 1 day |
| Exosome Therapy | Exosome growth-factor delivery | 40–60 min | Redness, hours to 1 day |
| Skinvive | Hyaluronic acid microdroplets | 10–25 min | Small marks 1–2 days |
Many patients combine treatments in one visit. Your doctor recommends a plan after examining your skin. See all skin boosters.
Your visit
From first message to flight home
-
Message us
Send your concern and travel dates on WhatsApp (+82-10-5719-2084), LINE or WeChat. A coordinator replies in English, Chinese, Japanese or Spanish.
-
Free doctor consultation
Skin analysis and photos, then a doctor confirms whether PDRN suits you. You get the plan and price in writing first.
-
Same-day treatment
PDRN Injection takes 30–45 minutes including numbing, in a private room, and most patients return to sightseeing the same day. Written aftercare in your language, plus WhatsApp follow-up once you are home.
Who reviewed this page
Dr. Seung-Jae Baek
Chief Medical Director · Korean medical licence No. 143338
JUVELOOK Meister & Speaker and Revinas Key Opinion Leader. Member of the Aesthetic Surgery & Laser Society (ASLS Korea), the Korean Academy of Obesity & Aesthetic Treatment (KOAT) and the Korea Filler Education and Research Academy. RE:BERRY Myeongdong is a KHIDI-registered foreign patient medical institution (Reg. No. M-2025-01-08-8519).
FAQ
PDRN Injection questions we hear every day
Does PDRN injection hurt?
Numbing cream is applied beforehand, so most patients feel light pricking. Areas over bone may feel slightly sharper.
How many PDRN sessions do I need?
Three to five sessions two to three weeks apart are typical for a noticeable change. Maintenance sessions every few months can help keep the result.
What is the difference between PDRN and Rejuran?
Both come from salmon DNA. PDRN uses shorter fragments focused on repair and calming, while Rejuran uses longer polynucleotide chains with more structural support. Your doctor can recommend one or combine both.
Can I have PDRN after a laser treatment?
Yes. PDRN is often used alongside or after lasers to support recovery and calm redness. Your doctor sets the timing based on the laser used.
Is there downtime after PDRN injection?
Mild redness and small bumps usually fade within hours to a day. Most patients can wear makeup the next day.
How much does PDRN injection cost in Myeongdong?
Price for PDRN injection depends on the area and number of sessions. The same price list applies to every nationality and is given to you in writing before treatment. See our skin booster price list.
Related treatments & guides
Thinking about PDRN Injection? Ask a doctor first.
58, Myeongdong 10-gil, Jung-gu, Seoul · 2 min from Myeongdong Station Exit 8 · Open daily, weekdays 10:30–20:00, weekends 10:30–19:00.
General information, not medical advice. Suitability for any treatment is decided at consultation.
